Dr. Marian Verbruggen describes how a soy isoflavone can help bone health, especially in women who want to prevent osteoporosis.
Maintain Your Bone Health with Soy
Interview with Dr. Marian Verbruggen
Interviewed by Raena Morgan
March 28, 2008
Raena Morgan: I’m visiting with Dr. Marian Verbruggen. She works with Frutarum Health and we’re talking about SoyLife, soybeans and the health benefits. Could you tell us about the isoflavone called diazden?
Dr. Marian Verbruggen: Well, in soy you have 3 main isoflavones; it’s genistein, diazden [and] glysitein. And, in the soy germ, by nature again, the diazden is very high, so it’s 50% to 60% isoflavones present in the soy germ [that] is diazden. In the past we didn’t know how to distinguish between the 3 isoflavones forms so they were just collected as one big group to show the health benefits. But nowadays you can distinguish a bit more and recent research actually shows that the diazden portion is of special interest in preventing bone [loss].
RM: Oh really?
MV: Yes. The diazden has been converted in your body to be effective, to become effective…it can be converted into a metabolite equal and equal is [a] much more potent phytoestrogen and it’s considered that this equal metabolite diazden is the active isoflavone for bone health.
RM: And so, these 3 isoflavones contribute to bone health?
MV: They all contribute to bone health but for diazden that seems to be a special effect, actually.
RM: More than the genistein?
MV: More than the genistein, yes.
RM: And, what was the other one, glysitein?
MV: Glysitein.
RM: Glysitein. But, the 3 together are very potent?
MV: They are potent, yes.
RM: And so, for women going through menopause who are experiencing bone thinning the diazden would be very potent for them?
MV: Yes. That’s a very important isoflavone for them for bone health.
RM: Thank you, Dr. Verbruggen.
MV: You’re welcome.



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